In Niagara Motel, a group of struggling individuals cross paths at a low-rent motel in the tourist Mecca of Niagara Falls. The main characters are: a knockout waitress being recruited to star in low budget porn videos, a young couple with a criminal past struggling to recover their child from social services, and a middle class husband and wife in a marriage that is disintegrating in near record time. The story also includes a woeful drunken motel manager (Craig Ferguson), and a prostitute working to support two small children. The needs of these people, their obvious failings and the unlucky conditions of their lives make them so vulnerable that they careen from the disturbing to the hilarious in a breathless instant. In this story, tragedy waltzes with unpredictable comedy in an intense dance of life.