Otherworldly villains are on the loose again, and it's up to Earth's interstellar police force to bring them to justice in this sequel to the sci-fi comedy blockbuster Men in Black. Agent Jay has become a high-ranking member of the Men in Black, the secret government task force designed to deal with unruly visitors from other worlds, while his former cohort. However, an especially nasty alien threat has reared its not-so-ugly head; Serleena is a shape-shifting Kylothian alien who is in pursuit of another escaped visitor who holds the key to powers that would allow her to destroy the world. Now it is up to the Men In Black to put an end to Serleena's plot for world Annihilation. They are Back in Black!